3okj | pdb_00003okj

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File:3okj.jpg

Template:STRUCTURE 3okj

Alpha-keto-aldehyde binding mechanism reveals a novel lead structure motif for proteasome inhibition

About this Structure

3okj is a 28 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  1. Grawert MA, Gallastegui N, Stein M, Schmidt B, Kloetzel PM, Huber R, Groll M. Elucidation of the alpha-keto-aldehyde binding mechanism: a lead structure motif for proteasome inhibition. Angew Chem Int Ed Engl. 2011 Jan 10;50(2):542-4. PMID:21154547 doi:10.1002/anie.201005488

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