3roc | pdb_00003roc

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Template:STRUCTURE 3roc

File:3roc.jpg

Crystal structure of human p38 alpha complexed with a pyrimidinone compound

Template:ABSTRACT PUBMED 21620699

About this Structure

3roc is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Devadas B, Selness SR, Xing L, Madsen HM, Marrufo LD, Shieh H, Messing DM, Yang JZ, Morgan HM, Anderson GD, Webb EG, Zhang J, Devraj RV, Monahan JB. Substituted N-aryl-6-pyrimidinones: A new class of potent, selective, and orally active p38 MAP kinase inhibitors. Bioorg Med Chem Lett. 2011 Jul 1;21(13):3856-60. Epub 2011 May 8. PMID:21620699 doi:10.1016/j.bmcl.2011.05.006

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