2fsd | pdb_00002fsd

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Revision as of 17:43, 29 January 2008 by OCA (talk | contribs) (New page: left|200px<br /><applet load="2fsd" size="350" color="white" frame="true" align="right" spinBox="true" caption="2fsd, resolution 2.30Å" /> '''A Common Fold for th...)
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2fsd, resolution 2.30Å

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A Common Fold for the Receptor Binding Domains of Lactococcal Phages? The Crystal Structure of the Head Domain of Phage bIL170

Overview

Lactococcus lactis, a gram-positive bacterium widely used by the dairy, industry, is subject to lytic phage infections. In the first step of, infection, phages recognize the host saccharidic receptor using their, receptor binding protein (RBP). Here, we report the 2.30-A-resolution, crystal structure of the RBP head domain from phage bIL170. The structure, of the head monomer is remarkably close to those of other lactococcal, phages, p2 and TP901-1, despite any sequence identity with them. The, knowledge of the three-dimensional structures of three RBPs gives a better, insight into the module exchanges which have occurred among phages.

About this Structure

2FSD is a Single protein structure of sequence from Unidentified phage. Full crystallographic information is available from OCA.

Reference

Crystal structure of the receptor-binding protein head domain from Lactococcus lactis phage bIL170., Ricagno S, Campanacci V, Blangy S, Spinelli S, Tremblay D, Moineau S, Tegoni M, Cambillau C, J Virol. 2006 Sep;80(18):9331-5. PMID:16940545

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