1ca8 | pdb_00001ca8

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Template:STRUCTURE 1ca8

File:1ca8.png

Thrombin inhibitors with rigid tripeptidyl aldehydes

Template:ABSTRACT PUBMED 9724521

About this Structure

1ca8 is a 3 chain structure with sequence from Hirudo medicinalis and Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Krishnan R, Zhang E, Hakansson K, Arni RK, Tulinsky A, Lim-Wilby MS, Levy OE, Semple JE, Brunck TK. Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes. Biochemistry. 1998 Sep 1;37(35):12094-103. PMID:9724521 doi:https://dx.doi.org/10.1021/bi980840e

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