3qlz | pdb_00003qlz
From Proteopedia
Candida glabrata dihydrofolate reductase complexed with NADPH and 5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-propylpyrimidine-2,4-diamine (UCP130B)
About this Structure
3qlz is a 2 chain structure with sequence from Candida glabrata. Full crystallographic information is available from OCA.
Reference
- Paulsen JL, Bendel SD, Anderson AC. Crystal structures of Candida albicans dihydrofolate reductase bound to propargyl-linked antifolates reveal the flexibility of active site loop residues critical for ligand potency and selectivity. Chem Biol Drug Des. 2011 Jul 5. doi: 10.1111/j.1747-0285.2011.01169.x. PMID:21726415 doi:10.1111/j.1747-0285.2011.01169.x
