3ooz | pdb_00003ooz
From Proteopedia
Bace1 in complex with the aminohydantoin Compound 102
Template:ABSTRACT PUBMED 20880704
About this Structure
3ooz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Malamas MS, Robichaud A, Erdei J, Quagliato D, Solvibile W, Zhou P, Morris K, Turner J, Wagner E, Fan K, Olland A, Jacobsen S, Reinhart P, Riddell D, Pangalos M. Design and synthesis of aminohydantoins as potent and selective human beta-secretase (BACE1) inhibitors with enhanced brain permeability. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6597-605. Epub 2010 Sep 15. PMID:20880704 doi:10.1016/j.bmcl.2010.09.029
