3p89 | pdb_00003p89

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File:3p89.jpg

Template:STRUCTURE 3p89

FXR bound to a quinolinecarboxylic acid

Template:ABSTRACT PUBMED 21256005

About this Structure

3p89 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Bass JY, Caravella JA, Chen L, Creech KL, Deaton DN, Madauss KP, Marr HB, McFadyen RB, Miller AB, Mills WY, Navas F 3rd, Parks DJ, Smalley TL Jr, Spearing PK, Todd D, Williams SP, Wisely GB. Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1206-13. Epub 2010 Dec 23. PMID:21256005 doi:10.1016/j.bmcl.2010.12.089

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