Complexes

Multi-protein assemblies

Many PDB files contain complexes in which a biological molecule is interacting with another biological molecule in a complex or assembly. These interactions, if biologically relevant, can be immensely insightful in shedding light on cellular and extracellular processes.

See Also

• Crystal contacts
• X-ray crystallography
• Biological assembly
• Multi-protein assemblies
• Ligand

Examples

• Ribosome
• T7 RNA Polymerase
• Mouse Toll-like receptor bound to dsRNA
• Human Follicle-Stimulating Hormone Complexed with its Receptor
• Platelet-receptor glycoprotein Ib alpha bound to the von Willebrand Factor A1 Domain
• Plant Viral Protein p19 Suppression of RNA Silencing
• RecG Bound to Three-Way DNA Junction

External Resources

• PICCOLO, a comprehensive relational database featuring the details of structurally characterized protein-protein interactions.
• PRO provides an ontological representation of proteins in complexes and is working to implement logical and consistent representation of protein complexes.

Literature Citations

Literature citations will be found at the respective servers linked above.

Proteopedia Page Contributors and Editors (what is this?)

Wayne Decatur