Complexes
From Proteopedia
Multi-protein assemblies
Many PDB files contain complexes in which a biological molecule is interacting with another biological molecule in a complex or assembly. These interactions, if biologically relevant, can be immensely insightful in shedding light on cellular and extracellular processes.
Examples
- Ribosome
- T7 RNA Polymerase
- Mouse Toll-like receptor bound to dsRNA
- Human Follicle-Stimulating Hormone Complexed with its Receptor
- Platelet-receptor glycoprotein Ib alpha bound to the von Willebrand Factor A1 Domain
- Plant Viral Protein p19 Suppression of RNA Silencing
- RecG Bound to Three-Way DNA Junction
See Also
External Resources
- PICCOLO, a comprehensive relational database featuring the details of structurally characterized protein-protein interactions.
- PRO provides an ontological representation of proteins in complexes. In particular, the authors are working to implement logical and consistent representation of protein complexes.
- COCOMAPS (bioCOmplexes COntact MAPS) is a web server for analysis and visualization of the interfaces present in biological complexes, such as protein-protein, protein-DNA and protein-RNA complexes, making use of intermolecular contact maps.
- The HADDOCK web server is web server for data-driven biomolecular docking for modeling of biomolecular complexes.
Literature Citations
Literature citations can be found at the respective servers linked above.
