Multi-protein assemblies
From Proteopedia
Many PDB files contain complexes in which a particular protein is interacting with a different protein in what are called multi-protein assemblies or multi-protein complexes. These interactions, if biologically relevant, can be immensely insightful in shedding light on cellular and extracellular processes.
Examples
- Ribosome
- Human Follicle-Stimulating Hormone Complexed with its Receptor
- Platelet-receptor glycoprotein Ib alpha bound to the von Willebrand Factor A1 Domain
See Also
- Complexes
- Assemblies
- Biological unit
- Biological assembly
- Crystal contacts
- X-ray crystallography
- Ligand
External Resources
- PICCOLO, a comprehensive relational database featuring the details of structurally characterized protein-protein interactions.
- PRO provides an ontological representation of proteins in complexes. In particular, the authors are working to implement logical and consistent representation of protein complexes.
- COCOMAPS (bioCOmplexes COntact MAPS) is a web server for analysis and visualization of the interfaces present in biological complexes, such as protein-protein, protein-DNA and protein-RNA complexes, making use of intermolecular contact maps.
- The HADDOCK web server is web server for data-driven biomolecular docking for modeling of biomolecular complexes.
Literature Citations
Literature citations can also be found at the respective servers linked above.
