3sfy | pdb_00003sfy

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Template:STRUCTURE 3sfy

File:3sfy.png

Cryptococcus neoformans protein farnesyltransferase in complex with FPT-II and ethylenediamine inhibitor 2

Template:ABSTRACT PUBMED 21816822

About this Structure

3sfy is a 2 chain structure with sequence from Cryptococcus neoformans. Full crystallographic information is available from OCA.

Reference

  1. Hast MA, Nichols CB, Armstrong SM, Kelly SM, Hellinga HW, Alspaugh JA, Beese LS. Structures of Cryptococcus neoformans Protein Farnesyltransferase Reveal Strategies for Developing Inhibitors That Target Fungal Pathogens. J Biol Chem. 2011 Oct 7;286(40):35149-62. Epub 2011 Aug 4. PMID:21816822 doi:10.1074/jbc.M111.250506

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OCA

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