2yit | pdb_00002yit

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File:2yit.png

Template:STRUCTURE 2yit

STRUCTURAL ANALYSIS OF CHECKPOINT KINASE 2 IN COMPLEX WITH PV1162, A NOVEL INHIBITOR

Template:ABSTRACT PUBMED 21907711

About this Structure

2yit is a 1 chain structure of Serine/threonine protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Lountos GT, Jobson AG, Tropea JE, Self CR, Zhang G, Pommier Y, Shoemaker RH, Waugh DS. X-ray structures of checkpoint kinase 2 in complex with inhibitors that target its gatekeeper-dependent hydrophobic pocket. FEBS Lett. 2011 Oct 20;585(20):3245-9. Epub 2011 Sep 7. PMID:21907711 doi:10.1016/j.febslet.2011.08.050
  2. Lountos GT, Tropea JE, Zhang D, Jobson AG, Pommier Y, Shoemaker RH, Waugh DS. Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor. Protein Sci. 2009 Jan;18(1):92-100. PMID:19177354 doi:10.1002/pro.16

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