3t9i | pdb_00003t9i

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File:3t9i.png

Template:STRUCTURE 3t9i

Pim1 complexed with a novel 3,6-disubstituted indole at 2.6 Ang Resolution

Template:ABSTRACT PUBMED 21945284

About this Structure

3t9i is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Nishiguchi GA, Atallah G, Bellamacina C, Burger MT, Ding Y, Feucht PH, Garcia PD, Han W, Klivansky L, Lindvall M. Discovery of novel 3,5-disubstituted indole derivatives as potent inhibitors of Pim-1, Pim-2, and Pim-3 protein kinases. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6366-9. Epub 2011 Sep 10. PMID:21945284 doi:10.1016/j.bmcl.2011.08.105

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