2wxv | pdb_00002wxv

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Template:STRUCTURE 2wxv

File:2wxv.png

STRUCTURE OF CDK2-CYCLIN A WITH A PYRAZOLO(4,3-H) QUINAZOLINE-3-CARBOXAMIDE INHIBITOR

Template:ABSTRACT PUBMED 20141146

About this Structure

2wxv is a 4 chain structure of Cell Division Protein Kinase 2 and Cyclin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Traquandi G, Ciomei M, Ballinari D, Casale E, Colombo N, Croci V, Fiorentini F, Isacchi A, Longo A, Mercurio C, Panzeri A, Pastori W, Pevarello P, Volpi D, Roussel P, Vulpetti A, Brasca MG. Identification of Potent Pyrazolo[4,3-h]quinazoline-3-carboxamides as Multi-Cyclin-Dependent Kinase Inhibitors (dagger). J Med Chem. 2010 Feb 8. PMID:20141146 doi:10.1021/jm901710h

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