Amyloid beta

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<StructureSection load=1iyt size='500' side='right' caption='amyloid-beta(1-42)', (1dm0)' scene=>

Introduction

Amyloids are insoluble fibrous proteins

The most reasonable structure determined structure consists of two helices, the first helix (residues 8-25) is well debined and has an RMSD of 0.38 angstroms while the second (residues 28-38) is interrupted at the Ile32-Gly33 connection connected by a kink (residues 26 and 27).

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Laura Olney, Alexander Berchansky, Michal Harel