4a55 | pdb_00004a55

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File:4a55.jpg

Template:STRUCTURE 4a55

Crystal structure of p110alpha in complex with iSH2 of p85alpha and the inhibitor PIK-108

Template:ABSTRACT PUBMED 22120714

About this Structure

4a55 is a 2 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Hon WC, Berndt A, Williams RL. Regulation of lipid binding underlies the activation mechanism of class IA PI3-kinases. Oncogene. 2011 Nov 28. doi: 10.1038/onc.2011.532. PMID:22120714 doi:10.1038/onc.2011.532

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OCA

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