3ude | pdb_00003ude

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File:3ude.jpg

Template:STRUCTURE 3ude

Crystal structure of E. coli HPPK in complex with bisubstrate analogue inhibitor J1B

Template:ABSTRACT PUBMED 22169600

About this Structure

3ude is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Shi G, Shaw G, Liang YH, Subburaman P, Li Y, Wu Y, Yan H, Ji X. Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: New design with improved properties. Bioorg Med Chem. 2012 Jan 1;20(1):47-57. Epub 2011 Nov 23. PMID:22169600 doi:10.1016/j.bmc.2011.11.032
  2. Shi G, Blaszczyk J, Ji X, Yan H. Bisubstrate analogue inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: synthesis and biochemical and crystallographic studies. J Med Chem. 2001 Apr 26;44(9):1364-71. PMID:11311059

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