2yau | pdb_00002yau

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File:2yau.png

Template:STRUCTURE 2yau

X-ray structure of the Leishmania infantum tryopanothione reductase in complex with auranofin

Template:ABSTRACT PUBMED 21833767

About this Structure

2yau is a 2 chain structure with sequence from Leishmania infantum. Full crystallographic information is available from OCA.

Reference

  1. Ilari A, Baiocco P, Messori L, Fiorillo A, Boffi A, Gramiccia M, Di Muccio T, Colotti G. A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition. Amino Acids. 2011 Aug 11. PMID:21833767 doi:10.1007/s00726-011-0997-9

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