2x9d | pdb_00002x9d

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File:2x9d.png

Template:STRUCTURE 2x9d

Tet repressor (class D) in complex with iso-7-chlortetracycline

Template:ABSTRACT PUBMED 21699184

About this Structure

2x9d is a 1 chain structure with sequence from Escherichia coli. This structure supersedes the now removed PDB entry 1du7. Full crystallographic information is available from OCA.

Reference

  1. Volkers G, Petruschka L, Hinrichs W. Recognition of drug degradation products by target proteins: isotetracycline binding to Tet repressor. J Med Chem. 2011 Jul 28;54(14):5108-15. Epub 2011 Jul 1. PMID:21699184 doi:10.1021/jm200332e
  2. Hinrichs W, Kisker C, Duvel M, Muller A, Tovar K, Hillen W, Saenger W. Structure of the Tet repressor-tetracycline complex and regulation of antibiotic resistance. Science. 1994 Apr 15;264(5157):418-20. PMID:8153629

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