4a5s | pdb_00004a5s
From Proteopedia
CRYSTAL STRUCTURE OF HUMAN DPP4 IN COMPLEX WITH A NOVAL HETEROCYCLIC DPP4 INHIBITOR
Template:ABSTRACT PUBMED 22177783
About this Structure
4a5s is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Sutton JM, Clark DE, Dunsdon SJ, Fenton G, Fillmore A, Harris NV, Higgs C, Hurley CA, Krintel SL, Mackenzie RE, Duttaroy A, Gangl E, Maniara W, Sedrani R, Namoto K, Ostermann N, Gerhartz B, Sirockin F, Trappe J, Hassiepen U, Baeschlin DK. Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetes. Bioorg Med Chem Lett. 2012 Feb 1;22(3):1464-8. Epub 2011 Nov 20. PMID:22177783 doi:10.1016/j.bmcl.2011.11.054
Proteopedia Page Contributors and Editors (what is this?)
Categories:
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- Dipeptidyl-peptidase IV
- Homo sapiens
- Baeschlin, D K.
- Clark, D E.
- Dunsdon, S J.
- Duttaroy, A.
- Fenton, G.
- Fillmore, A.
- Gangl, E.
- Gerhartz, B.
- Harris, N V.
- Hassiepen, U.
- Higgs, C.
- Hurley, C A.
- Krintel, S L.
- Kroemer, M.
- Mackenzie, R E.
- Maniara, W.
- Namoto, K.
- Ostermann, N.
- Sedrani, R.
- Sirockin, F.
- Sutton, J M.
- Trappe, J.
- Zink, F.
- Hydrolase
- Novartis compound nvp-biv988
- Type 2 diabetes
