2pzp | pdb_00002pzp

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File:2pzp.png

Template:STRUCTURE 2pzp

Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic K526E Mutation Responsible for Crouzon Syndrome

Template:ABSTRACT PUBMED 17803937

About this Structure

2pzp is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Chen H, Ma J, Li W, Eliseenkova AV, Xu C, Neubert TA, Miller WT, Mohammadi M. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol Cell. 2007 Sep 7;27(5):717-30. PMID:17803937 doi:https://dx.doi.org/10.1016/j.molcel.2007.06.028

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