2pwl | pdb_00002pwl
From Proteopedia
Crystal Strucure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic N549H Mutation Responsible for Crouzon Syndrome.
About this Structure
2pwl is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Chen H, Ma J, Li W, Eliseenkova AV, Xu C, Neubert TA, Miller WT, Mohammadi M. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. Mol Cell. 2007 Sep 7;27(5):717-30. PMID:17803937 doi:https://dx.doi.org/10.1016/j.molcel.2007.06.028
