3byz | pdb_00003byz
From Proteopedia
2-Amino-1,3-thiazol-4(5H)-ones as Potent and Selective 11-Hydroxysteroid Dehydrogenase Type 1 Inhibitors
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About this Structure
3BYZ is a Single protein structure of sequence from Homo sapiens with NDP and H11 as ligands. Active as 11-beta-hydroxysteroid dehydrogenase, with EC number 1.1.1.146 Known structural/functional Sites: AC1, AC2, AC3, AC4, AC5, AC6, AC7 and AC8. Full crystallographic information is available from OCA.
Page seeded by OCA on Wed Feb 13 08:24:15 2008
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- 11-beta-hydroxysteroid dehydrogenase
- Homo sapiens
- Single protein
- Jordan, S.R.
- Li, V.
- Zhang, J.
- H11
- NDP
- ----
- 3-layer (aba) sandwich
- Alpha beta
- Endoplasmic reticulum
- Glycoprotein
- Lipid metabolism
- Membrane
- Microsome
- Nad(p)-binding rossmann-like domain. amino thiazole inhibitor
- Nadp
- Oxidoreductase
- Polymorphism
- Rossmann fold
- Signal-anchor
- Steroid metabolism
- Transmembrane