4dv8 | pdb_00004dv8

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File:4dv8.jpg

Template:STRUCTURE 4dv8

Anthrax Lethal Factor metalloproteinase in complex with the Hydroxamic acid based small molecule PT8421

Template:ABSTRACT PUBMED 22342144

About this Structure

4dv8 is a 1 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

Reference

  1. Jiao GS, Kim S, Moayeri M, Crown D, Thai A, Cregar-Hernandez L, McKasson L, Sankaran B, Lehrer A, Wong T, Johns L, Margosiak SA, Leppla SH, Johnson AT. Antidotes to anthrax lethal factor intoxication. Part 3: Evaluation of core structures and further modifications to the C2-side chain. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2242-6. Epub 2012 Feb 1. PMID:22342144 doi:10.1016/j.bmcl.2012.01.095

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