3tyn | pdb_00003tyn

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File:3tyn.jpg

Template:STRUCTURE 3tyn

Structure of neuronal nitric oxide synthase heme domain in complex with 2-(((2-(((3S,4S)-4-((6-amino-4-methylpyridin-2-yl)methyl)pyrrolidin-3-yl)oxy)ethyl)amino)methyl)phenol

Template:ABSTRACT PUBMED 22370337

About this Structure

3tyn is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  1. Labby KJ, Xue F, Kraus JM, Ji H, Mataka J, Li H, Martasek P, Roman LJ, Poulos TL, Silverman RB. Intramolecular hydrogen bonding: A potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase. Bioorg Med Chem. 2012 Feb 7. PMID:22370337 doi:10.1016/j.bmc.2012.01.037

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