4ago | pdb_00004ago

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Template:STRUCTURE 4ago

File:4ago.jpg

Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan5174

Template:ABSTRACT PUBMED 17015838

About this Structure

4ago is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Joerger AC, Ang HC, Fersht AR. Structural basis for understanding oncogenic p53 mutations and designing rescue drugs. Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15056-61. Epub 2006 Oct 2. PMID:17015838

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OCA

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