3zrc | pdb_00003zrc

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Template:STRUCTURE 3zrc

File:3zrc.png

pVHL54-213-EloB-EloC complex (4R)-4-HYDROXY-1-[(3-METHYLISOXAZOL-5-YL)ACETYL]-N-[4-(1,3-OXAZOL-5-YL)BENZYL]-L-PROLINAMIDE bound

Template:ABSTRACT PUBMED 22369643

About this Structure

3zrc is a 12 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Buckley DL, Van Molle I, Gareiss PC, Tae HS, Michel J, Noblin DJ, Jorgensen WL, Ciulli A, Crews CM. Targeting the von Hippel-Lindau E3 Ubiquitin Ligase Using Small Molecules To Disrupt the VHL/HIF-1alpha Interaction. J Am Chem Soc. 2012 Mar 14;134(10):4465-8. Epub 2012 Feb 27. PMID:22369643 doi:10.1021/ja209924v

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OCA

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