3ufn | pdb_00003ufn

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Template:STRUCTURE 3ufn

File:3ufn.jpg

Crystal Structure of Multidrug Resistant HIV-1 Protease Clinical Isolate PR20 in Complex with Saquinavir

Template:ABSTRACT PUBMED 22404139

About this Structure

3ufn is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Agniswamy J, Shen CH, Aniana A, Sayer JM, Louis JM, Weber IT. HIV-1 Protease with 20 Mutations Exhibits Extreme Resistance to Clinical Inhibitors through Coordinated Structural Rearrangements. Biochemistry. 2012 Mar 20. PMID:22404139 doi:10.1021/bi2018317

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