3aox | pdb_00003aox

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Template:STRUCTURE 3aox

File:3aox.png

X-ray crystal structure of human anaplastic lymphoma kinase in complex with CH5424802

Template:ABSTRACT PUBMED 21575866

About this Structure

3aox is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Sakamoto H, Tsukaguchi T, Hiroshima S, Kodama T, Kobayashi T, Fukami TA, Oikawa N, Tsukuda T, Ishii N, Aoki Y. CH5424802, a selective ALK inhibitor capable of blocking the resistant gatekeeper mutant. Cancer Cell. 2011 May 17;19(5):679-90. PMID:21575866 doi:10.1016/j.ccr.2011.04.004

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