4alh | pdb_00004alh

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File:4alh.jpg

Template:STRUCTURE 4alh

N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 3,5 dimethyl-4-phenyl-1,2- oxazole

Template:ABSTRACT PUBMED 22136469

About this Structure

4alh is a 3 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 4a9p. Full crystallographic information is available from OCA.

Reference

  1. Bamborough P, Diallo H, Goodacre JD, Gordon L, Lewis A, Seal JT, Wilson DM, Woodrow MD, Chung CW. Fragment-based discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides. J Med Chem. 2012 Jan 26;55(2):587-96. Epub 2012 Jan 11. PMID:22136469 doi:10.1021/jm201283q

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