4abj | pdb_00004abj

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Template:STRUCTURE 4abj

File:4abj.png

Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (IcA)SFTI-1(1,14), that was 1,5-disubstituted with 1,2,3- trizol to mimic a cis amid bond

Template:ABSTRACT PUBMED 22374650

About this Structure

4abj is a 2 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  1. Tischler M, Nasu D, Empting M, Schmelz S, Heinz DW, Rottmann P, Kolmar H, Buntkowsky G, Tietze D, Avrutina O. Braces for the Peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations. Angew Chem Int Ed Engl. 2012 Apr 10;51(15):3708-12. doi: 10.1002/anie.201108983. , Epub 2012 Feb 28. PMID:22374650 doi:10.1002/anie.201108983

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