3s9y | pdb_00003s9y

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File:3s9y.jpg

Template:STRUCTURE 3s9y

Crystal Structure of P. falciparum orotidine 5'-monophosphate decarboxylase complexed with 5-fluoro-6-amino-UMP in space group P21, produced from 5-fluoro-6-azido-UMP

Template:ABSTRACT PUBMED 19260677

About this Structure

3s9y is a 4 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA.

Reference

  1. Bello AM, Konforte D, Poduch E, Furlonger C, Wei L, Liu Y, Lewis M, Pai EF, Paige CJ, Kotra LP. Structure-activity relationships of orotidine-5'-monophosphate decarboxylase inhibitors as anticancer agents. J Med Chem. 2009 Mar 26;52(6):1648-58. PMID:19260677 doi:10.1021/jm801224t

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OCA

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