Interferon

spinqualitylabelsall models Click on the green links to the left to view the structural aspects of interferons. PDB ID: 2hym) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Interferon-β Interferon-β is a protein growth factor that stimulates an antiviral defense. Its encoding gene is one of only two known vertebrate structural genes that lacks introns. Interferon-β is a relatively simple biological response modifier, with several identifiable regions. It consists of five alpha helices, as well as multiple interconnecting loop regions. Helices A, B and D run parallel to one another, and helices C and E run anti-parallel to the other three helices, but parallel to one another. Helix A consists of residues 6-23; Helix B consists of residues 49-65; Helix C consists of residues 77-91; Helix D consists of residues 112-131; and Helix E consists of residues 135-155.

A comparative representation of three interferons

spinqualitylabelsall models Interferon Alpha Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D

spinqualitylabelsall models Interferon Beta Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D

Synchronize the three applets showing interferons alpha, beta, and gamma by clicking the checkbox

Proteopedia Page Contributors and Editors (what is this?)

Alexander Berchansky, Kirsten Eldredge, Karl Oberholser, Michal Harel, Joel L. Sussman, Jaime Prilusky