4dem | pdb_00004dem

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File:4dem.png

Template:STRUCTURE 4dem

Crystal structure of human FPPS in complex with YS_04_70

Template:ABSTRACT PUBMED 22390415

About this Structure

4dem is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Lin YS, Park J, De Schutter JW, Huang XF, Berghuis AM, Sebag M, Tsantrizos YS. Design and Synthesis of Active Site Inhibitors of the Human Farnesyl Pyrophosphate Synthase: Apoptosis and Inhibition of ERK Phosphorylation in Multiple Myeloma Cells. J Med Chem. 2012 Mar 19. PMID:22390415 doi:10.1021/jm201657x

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