4dl6 | pdb_00004dl6

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File:4dl6.jpg

Template:STRUCTURE 4dl6

Human DNA polymerase eta extending primer immediately after cisplatin crosslink (Pt-GG3).

Template:ABSTRACT PUBMED 22529383

About this Structure

4dl6 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Zhao Y, Biertumpfel C, Gregory MT, Hua YJ, Hanaoka F, Yang W. Structural basis of human DNA polymerase eta-mediated chemoresistance to cisplatin. Proc Natl Acad Sci U S A. 2012 Apr 23. PMID:22529383 doi:10.1073/pnas.1202681109

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