4a6b | pdb_00004a6b

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Template:STRUCTURE 4a6b

File:4a6b.jpg

Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors

Template:ABSTRACT PUBMED 22376008

About this Structure

4a6b is a 2 chain structure with sequence from Human immunodeficiency virus. Full crystallographic information is available from OCA.

Reference

  1. Wu X, Ohrngren P, Joshi AA, Trejos A, Persson M, Arvela RK, Wallberg H, Vrang L, Rosenquist A, Samuelsson BB, Unge J, Larhed M. Synthesis, X-ray analysis, and biological evaluation of a new class of stereopure lactam-based HIV-1 protease inhibitors. J Med Chem. 2012 Mar 22;55(6):2724-36. Epub 2012 Mar 13. PMID:22376008 doi:10.1021/jm201620t

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OCA

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