3rbm | pdb_00003rbm

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File:3rbm.png

Template:STRUCTURE 3rbm

Crystal structure of Plasmodium vivax geranylgeranylpyrophosphate synthase complexed with BPH -703

Template:ABSTRACT PUBMED 22392982

About this Structure

3rbm is a 4 chain structure with sequence from Plasmodium vivax. Full crystallographic information is available from OCA.

Reference

  1. No JH, de Macedo Dossin F, Zhang Y, Liu YL, Zhu W, Feng X, Yoo JA, Lee E, Wang K, Hui R, Freitas-Junior LH, Oldfield E. Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4058-63. Epub 2012 Mar 5. PMID:22392982 doi:10.1073/pnas.1118215109

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