3ryw | pdb_00003ryw

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File:3ryw.jpg

Template:STRUCTURE 3ryw

Crystal structure of P. vivax geranylgeranyl diphosphate synthase complexed with BPH-811

Template:ABSTRACT PUBMED 22392982

About this Structure

3ryw is a 4 chain structure with sequence from Plasmodium vivax. Full crystallographic information is available from OCA.

Reference

  1. No JH, de Macedo Dossin F, Zhang Y, Liu YL, Zhu W, Feng X, Yoo JA, Lee E, Wang K, Hui R, Freitas-Junior LH, Oldfield E. Lipophilic analogs of zoledronate and risedronate inhibit Plasmodium geranylgeranyl diphosphate synthase (GGPPS) and exhibit potent antimalarial activity. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4058-63. Epub 2012 Mar 5. PMID:22392982 doi:10.1073/pnas.1118215109

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