4eox | pdb_00004eox

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File:4eox.jpg

Template:STRUCTURE 4eox

X-ray Structure of Polypeptide Deformylase Bound to a Acylprolinamide inhibitor

Template:ABSTRACT PUBMED 22579486

About this Structure

4eox is a 1 chain structure with sequence from Streptococcus pneumoniae. Full crystallographic information is available from OCA.

Reference

  1. Axten JM, Medina JR, Blackledge CW, Duquenne C, Grant SW, Bobko MA, Peng T, Miller WH, Pinckney T, Gallagher TF, Kulkarni S, Lewandowski T, Van Aller GS, Zonis R, Ward P, Campobasso N. Acylprolinamides: A new class of peptide deformylase inhibitors with in vivo antibacterial activity. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4028-32. Epub 2012 Apr 25. PMID:22579486 doi:10.1016/j.bmcl.2012.04.086

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