2ah2 | pdb_00002ah2

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File:2ah2.png

Template:STRUCTURE 2ah2

Trypanosoma cruzi trans-sialidase in complex with 2,3-difluorosialic acid (covalent intermediate)

Template:ABSTRACT PUBMED 15130470

About this Structure

2ah2 is a 1 chain structure with sequence from Trypanosoma cruzi. This structure supersedes the now removed PDB entry 1s0k. Full crystallographic information is available from OCA.

Reference

  1. Amaya MF, Watts AG, Damager I, Wehenkel A, Nguyen T, Buschiazzo A, Paris G, Frasch AC, Withers SG, Alzari PM. Structural insights into the catalytic mechanism of Trypanosoma cruzi trans-sialidase. Structure. 2004 May;12(5):775-84. PMID:15130470 doi:https://dx.doi.org/10.1016/j.str.2004.02.036
  2. Demir O, Roitberg AE. Modulation of catalytic function by differential plasticity of the active site: case study of Trypanosoma cruzi trans-sialidase and Trypanosoma rangeli sialidase. Biochemistry. 2009 Apr 21;48(15):3398-406. PMID:19216574 doi:10.1021/bi802230y

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