3bmo | pdb_00003bmo

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File:3bmo.png

Template:STRUCTURE 3bmo

Structure of Pteridine Reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor (Compound AX4)

Template:ABSTRACT PUBMED 19916554

About this Structure

3bmo is a 4 chain structure with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.

Reference

  1. Tulloch LB, Martini VP, Iulek J, Huggan JK, Lee JH, Gibson CL, Smith TK, Suckling CJ, Hunter WN. Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases. J Med Chem. 2009 Nov 16. PMID:19916554 doi:10.1021/jm901059x

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OCA

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