3k1o | pdb_00003k1o
From Proteopedia
Crystal structure of sterol 14-alpha demethylase (CYP51) from Trypanosoma cruzi in complex with a potential antichagasic drug, posaconazole
About this Structure
3k1o is a 1 chain structure with sequence from Trypanosoma cruzi. Full crystallographic information is available from OCA.
Reference
- Lepesheva GI, Hargrove TY, Anderson S, Kleshchenko Y, Furtak V, Wawrzak Z, Villalta F, Waterman MR. Structural insights into inhibition of sterol 14alpha-demethylase in the human pathogen Trypanosoma cruzi. J Biol Chem. 2010 Aug 13;285(33):25582-90. Epub 2010 Jun 8. PMID:20530488 doi:10.1074/jbc.M110.133215
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Sterol 14-demethylase
- Trypanosoma cruzi
- Anderson, S.
- Hargrove, T Y.
- Lepesheva, G I
- Waterman, M R.
- Wawrzak, Z.
- Cyp51
- Cytochrome p450
- Eburicol 14a-demethylase
- Endoplasmic reticulum
- Heme
- Heme-thiolate protein
- Iron
- Lipid
- Membrane
- Monooxygenase
- Oxidoreductase
- Sterol 14-alpha demethylase
- Sterol biosynthesis
- Transmembrane protein
