2x0n | pdb_00002x0n

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Template:ABSTRACT PUBMED 8460146


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2x0n, resolution 3.20Å (default scene)
Sites: AC1, AC2, AC3, AC4, AC5, AC6, AC7, AC8, AC9, BC1, BC2, BC3, BC4, BC5, BC6, BC7, BC8 and BC9
Ligands: NAD, SO4
Activity: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating), with EC number 1.2.1.12
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



STRUCTURE OF GLYCOSOMAL GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE FROM TRYPANOSOMA BRUCEI DETERMINED FROM LAUE DATA

About this Structure

2x0n is a 6 chain structure with sequence from Trypanosoma brucei brucei. This structure supersedes the now removed PDB entry 1gga. Full crystallographic information is available from OCA.

Reference

  1. Vellieux FM, Hajdu J, Verlinde CL, Groendijk H, Read RJ, Greenhough TJ, Campbell JW, Kalk KH, Littlechild JA, Watson HC, et al.. Structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma brucei determined from Laue data. Proc Natl Acad Sci U S A. 1993 Mar 15;90(6):2355-9. PMID:8460146
  2. Vellieux FM, Hajdu J, Hol WG. Refined 3.2 A structure of glycosomal holo glyceraldehyde phosphate dehydrogenase from Trypanosoma brucei brucei. Acta Crystallogr D Biol Crystallogr. 1995 Jul 1;51(Pt 4):575-89. PMID:15299846 doi:10.1107/S0907444995003015
  3. Read RJ, Wierenga RK, Groendijk H, Hol WG, Lambeir A, Opperdoes FR. Preliminary crystallographic studies of glycosomal glyceraldehyde phosphate dehydrogenase from Trypanosoma brucei brucei. J Mol Biol. 1987 Apr 5;194(3):573-5. PMID:3625777
  4. Michels PA, Poliszczak A, Osinga KA, Misset O, Van Beeumen J, Wierenga RK, Borst P, Opperdoes FR. Two tandemly linked identical genes code for the glycosomal glyceraldehyde-phosphate dehydrogenase in Trypanosoma brucei. EMBO J. 1986 May;5(5):1049-56. PMID:3013612

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