2fvj | pdb_00002fvj

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Template:STRUCTURE 2fvj

File:2fvj.png

A novel anti-adipogenic partial agonist of peroxisome proliferator-activated receptor-gamma (PPARG) recruits pparg-coactivator-1 alpha (PGC1A) but potentiates insulin signaling in vitro

Template:ABSTRACT PUBMED 16373399

About this Structure

2fvj is a 2 chain structure of Peroxisome Proliferator-Activated Receptors with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Burgermeister E, Schnoebelen A, Flament A, Benz J, Stihle M, Gsell B, Rufer A, Ruf A, Kuhn B, Marki HP, Mizrahi J, Sebokova E, Niesor E, Meyer M. A novel partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) recruits PPARgamma-coactivator-1alpha, prevents triglyceride accumulation, and potentiates insulin signaling in vitro. Mol Endocrinol. 2006 Apr;20(4):809-30. Epub 2005 Dec 22. PMID:16373399 doi:10.1210/me.2005-0171

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