1hti | pdb_00001hti

Ligands:

PGA

Activity:

Triose-phosphate isomerase, with EC number 5.3.1.1

Structural annotation:
Resources:	CATH : 1Htia00, 1Htib00 InterPro : Ipr000652, Ipr013785 Pfam : PF00121 SCOP : d1htia_, d1htib_ UniProt : P60174

Functional annotation:
Biological process:	glycolysis gluconeogenesis pentose-phosphate shunt fatty acid biosynthetic process lipid biosynthetic process metabolic process
Molecular function:	isomerase activity triose-phosphate isomerase activity catalytic activity

Evolutionary conservation:

Toggle Conservation Colors:	Rows = identical sequences:
Further Information:	Caveats, Explanation, Complete Results at ConSurfDB

Resources:

FirstGlance, OCA, RCSB, PDBsum

Coordinates:

save as pdb, mmCIF, xml

About this Structure

1hti is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Mande SC, Mainfroid V, Kalk KH, Goraj K, Martial JA, Hol WG. Crystal structure of recombinant human triosephosphate isomerase at 2.8 A resolution. Triosephosphate isomerase-related human genetic disorders and comparison with the trypanosomal enzyme. Protein Sci. 1994 May;3(5):810-21. PMID:8061610
Scheibel T, Bell S, Walke S. S. cerevisiae and sulfur: a unique way to deal with the environment. FASEB J. 1997 Sep;11(11):917-21. PMID:9285490