4aa5 | pdb_00004aa5

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Template:STRUCTURE 4aa5

File:4aa5.png

P38ALPHA MAP KINASE BOUND TO CMPD 33

Template:ABSTRACT PUBMED 22608965

About this Structure

4aa5 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Brown DS, Cumming JG, Bethel P, Finlayson J, Gerhardt S, Nash I, Pauptit RA, Pike KG, Reid A, Snelson W, Swallow S, Thompson C. The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]ben zamide (AZD6703), a clinical p38alpha MAP kinase inhibitor for the treatment of inflammatory diseases. Bioorg Med Chem Lett. 2012 Jun 15;22(12):3879-83. Epub 2012 May 2. PMID:22608965 doi:10.1016/j.bmcl.2012.04.116

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