3fxi | pdb_00003fxi

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Template:STRUCTURE 3fxi

File:3fxi.png

Crystal structure of the human TLR4-human MD-2-E.coli LPS Ra complex

Template:ABSTRACT PUBMED 19252480

About this Structure

3fxi is a 4 chain structure of Toll-like Receptors with sequence from Escherichia coli and Homo sapiens. The November 2011 RCSB PDB Molecule of the Month feature on Toll-like Receptors by David Goodsell is 10.2210/rcsb_pdb/mom_2011_11. Full crystallographic information is available from OCA.

See Also

Reference

  1. Park BS, Song DH, Kim HM, Choi BS, Lee H, Lee JO. The structural basis of lipopolysaccharide recognition by the TLR4-MD-2 complex. Nature. 2009 Apr 30;458(7242):1191-5. Epub 2009 Mar 1. PMID:19252480 doi:10.1038/nature07830
  2. Lin SC, Lo YC, Wu H. Helical assembly in the MyD88-IRAK4-IRAK2 complex in TLR/IL-1R signalling. Nature. 2010 Jun 17;465(7300):885-90. Epub 2010 May 19. PMID:20485341 doi:10.1038/nature09121

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