3vhl | pdb_00003vhl

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File:3vhl.jpg

Template:STRUCTURE 3vhl

Crystal structure of the DHR-2 domain of DOCK8 in complex with Cdc42 (T17N mutant)

Template:ABSTRACT PUBMED 22461490

About this Structure

3vhl is a 2 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Harada Y, Tanaka Y, Terasawa M, Pieczyk M, Habiro K, Katakai T, Hanawa-Suetsugu K, Kukimoto-Niino M, Nishizaki T, Shirouzu M, Duan X, Uruno T, Nishikimi A, Sanematsu F, Yokoyama S, Stein JV, Kinashi T, Fukui Y. DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses. Blood. 2012 May 10;119(19):4451-61. Epub 2012 Mar 28. PMID:22461490 doi:10.1182/blood-2012-01-407098

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