3vsw | pdb_00003vsw

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File:3vsw.jpg

Template:STRUCTURE 3vsw

Human renin in complex with compound 8

Template:ABSTRACT PUBMED 22726934

About this Structure

3vsw is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Nakamura Y, Sugita C, Meguro M, Miyazaki S, Tamaki K, Takahashi M, Nagai Y, Nagayama T, Kato M, Suemune H, Nishi T. Design and optimization of novel (2S,4S,5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxy-2-isop ropylhexanamides as renin inhibitors. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4561-6. Epub 2012 Jun 4. PMID:22726934 doi:10.1016/j.bmcl.2012.05.092

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