3vsx | pdb_00003vsx

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Template:STRUCTURE 3vsx

File:3vsx.jpg

Human renin in complex with compound 18

Template:ABSTRACT PUBMED 22726934

About this Structure

3vsx is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Nakamura Y, Sugita C, Meguro M, Miyazaki S, Tamaki K, Takahashi M, Nagai Y, Nagayama T, Kato M, Suemune H, Nishi T. Design and optimization of novel (2S,4S,5S)-5-amino-6-(2,2-dimethyl-5-oxo-4-phenylpiperazin-1-yl)-4-hydroxy-2-isop ropylhexanamides as renin inhibitors. Bioorg Med Chem Lett. 2012 Jul 15;22(14):4561-6. Epub 2012 Jun 4. PMID:22726934 doi:10.1016/j.bmcl.2012.05.092

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